김호철 교수
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2020 2020 1993 1987 |
2020 2020 1993 1987 |
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| 전문과정 | |
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2021 2017 2016 2015 2013 2007 |
KAIST 최고경영자과정 (AIM) 수료 경희대학교 와인・워터・티 마스터 소믈리에 전문가과정 수료 서울대학교 최고지도자 인문학과정(AFP) 수료 서강대학교 가톨릭경영자과정(SCAMP) 수료 보건산업진흥원 제약기업 최고경영자과정 수료 EBS-MS MBA 과정 수료 |
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경력 |
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2020 1993 2017 2008 - 2016 2012 - 2014 2011 - 2013 2009 - 2013 2010 - 2012 2011 – 2012 2011 2010 - 2011 2010 - 2011 2010 - 2011 2010 - 2011 2003 – 2011 2004 - 2006 2005 1999 - 2004 1990 - 1992 1987 - 1992 |
現 경희대학교 융합한의과학연구소장 現 경희대학교 한의과대학 본초학교실 교수 現 세계약선식료학회 부회장 식품의약품안전청 중앙약사심의위원회 위원 한국연구재단 기초연구본부 의약학단 전문위원(RB) 한국한의학교육평가원 이사 경희대 창업보육센터 운영위원 식품의약품안정청(KFDA) 의약품부작용심의위원회 위원 사단법인 대한한의사협회 부회장 식품의약품안전청장 표창 경희대학교 한의학연구소장 대한본초학회장 교육과학기술부 BK21 한의과학사업단장 경희대학교 한의과대학 연구부학장 (주) 뉴메드 대표이사 식품의약품안전청 건강기능식품심의위원회 위원 세계인명사전 '마르퀴스 후즈후' 등재 경희대학교 동서의학대학원 BK21 한방신약개발팀장 상지대, 대전대, 경원대 강사 경희대학교 한의과대학 조교 |
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| 초청교수 | |
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2020 2006 - 2008 1997 - 1999 1996 - 1996 1996 - 1997 1996 - 1997 1994 - 1995 |
중국 수도의과대학 중약감정연구실 객원교수 미국 존스홉킨스 의과대학 중풍센터 객원교수 미국코넬의과대학 신경분자생물학연구실 객원교수 중국산동성부속중의병원 제제과 객원교수 한국과학기술연구원(KIST) 객원연구원 식품의약품안전청(KFDA) 객원연구원 서울대학교 의과대학 약리학교실 객원교수 |
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| 학회활동 | |
| 대한본초학회 대한한의학회 대한약리학회 한국생약학회 한국뇌신경과학회 고려인삼학회 한국약용작물학회 한국식품영양과학회 Society for Neuroscience (SFN) International Society for Cerebral Blood Flow and Metabolism The Society for Medicinal Plant and Natural Product Research The American Society of Pharmacognosy (ASP) |
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| 특허 | |
| 1. 특허등록 Extract of Scutellariae Radix having neuroprotective effects and pharmaceutical preparations containing thesame 2002.11.28 (10-0364383) Novel phenyl derivatives, the process for preparing them and the pharmacological composition and the cosmetic composition containing them 2003.04 25 (10-0383366) Novel diphenyl amide derivatives, the process for preparing them and the pharmacological composition and the cosmetic composition containing them. 2003.11.18 (10-0407640) Extract of Acanthopanacis Cortex having neuroprotective effects and pharmaceutical composition containing the same 2004.12.03 (10-0458131) Extract of Acanthopanax senticosus having longitudinal bone growth promotive effects and pharmaceutical composition containing the same 2004. 12.14 (10-0463263) Composition comprising the extract of crude drug complex having neuronal cell-protecting activity for preventing and treating the degenerative brain disease 2006. 06.15 (10-0592488) Health care foods comprising Eleutheroside E having bone growth-promoting effects 2006.6.29(10-0597563) Pharmaceutical composition comprising the acetylshikonin having neuro-protective activity 2006.9.27 (10-0631432) Composition comprising the extract of Buddlejaofficinalis having neuronal cell-pretecting activity for preventing and treating degenerative brain disease 2006.11. 03 (10-0644773) Composition comprising oleic acid having neuronalcell-protecting activity for preventing and treating the degenerative brain disease 2007.09.03 (10-0756890) Functional food for preventing and ameliorating neurodegenerative disease comprising oleic acid having neuronal cell-protecting activity 2007.07. 31 (10-0746592) Pharmaceutical composition comprising gomisin-Ａ as aneffective ingredient showing neuro-protective activity 2007.11.27 (10-0781581) Composition comprising the extract of Viscum album var. coloratum for stimulating bone growth 2008.03.25 (10-0818204) Composition for treatment or prevention of inflammatory diseases 2008.0 4.18 (10-0825041) Composition comprising the extract of crude drug complex for stimulating bone growth 2008.07.14 (10-0847343) Composition for improving erectile dysfunction and erection maintenance containing the extract of crude drug complex 2008. 07.30 (10-0850503) Composition comprising the extract of crude drug complex for stimulating bone growth 2008.08.06 (10-0851855) Composition comprising the extracts of Puerariae Radix and the daidzein isolated from there as an active ingradient for prevention or treatment of ischemia 2008.08.26 (10-0855741) Composition comprising the extract of crude drug complex having neuroprotective activity for preventing and treating stroke and neurodegenerative diseases 2008.12.09 (10-0874187) Pharmaceutical composition comprising the extracts of root of Polygonum cuspidatum for neuroprotective effect. 2009.02.16. (10-08850730000) Pharmaceutical composition comprising the extracts of root of Polygonum cuspidatum for neuroprotective effect 2009.02.26 (10-0885073) Composition comprising Nodakenin having neuronal cell-protecting activity for preventing and treating the degenerative brain disease 2009.02.26 (10-0886948) Composition comprising the extract of crude drug complex for stimulating bone growth 2009.03.23 (10-0890991) Composition comprising the extract of crude drug complex for stimulating bone growth 2009.5.27 (10-0900836) The pharmaceutical composition comprising the extract of Astragalus membrancens Bunge or ethyl acetate fraction therefrom for treat and prevantion for bone growth trouble 2010.11.23 (10-0997215) Composition for improving erectile dysfunction and erection maintenance comprising the extract of Nelumbinis Semen 2011.03.17 (10-1024611) A composition for prevention and treatment of degenerative brain diseases comprising extracts or fractions of Metaplexis japonica as an active ingredient 2011.05.23 (10-1037776) Composition comprising the extract of crude drug complex having neuroprotective activity for preventing and treating stroke and neurodegenerative diseases 2011.08.24. (1 846 011 Germany) Composition comprising oleic acid and the use thereof 2012.06.05. (8,193,245 USA) Composition comprising oleic acid and the use 2012.05.18. (4993515 Japan) Composition comprising oleic acid and the use 2012.01.15. (ZL200680030221.7 China) Composition comprising the extract of crude drug complex having neuroprotective activity for preventing and treating stroke and neurodegenerative diseases 2012.08.14. (8,241,679 USA) The pharmaceutical composition comprising the extract of Astilbe chinesis for preventing and treating the degenerative brain disease. 2014.01.29. (10-13597600000) A composition comprising the complex extract for preventing or treating stroke and degenerative brain disease 2014.07.21 (10-1423875) A cosmetic composition comprising extracts of Rhynchosia nulubilis processed with Glycyrrhiza uralensis for whitening skin 2014.11.23 (10-1466551) A cosmetic composition comprising extracts of Rhynchosia nulubilis peel for whitening skin 2014.12.02 (10-1470707) A pharmaceutical composition comprising the extract of Sceptridium ternatum for preventing or treating stroke and degenerative brain disease 2014.12.26 (10-1478882) A composition comprising the complex extract of Rehmannia glutinosa and Pueraria lobata for preventing or treating female menopausal disorder 2015.01.21 (10-1486857) A cosmetic composition for improving skin wrinkle comprising extracts of steaming processed Rhynchosia nulubilis 2015.03.02 (10-1500044) A pharmaceutical composition comprising the combined extract of Pueraria lobata and Scutellaria baicalensis for preventing or treating stroke and degenerative brain disease 2015.08.21 (10-1548050) Anti-bacterial composition against bacteria related respiratory diseases, comprising essential oil from Abies holophylla 2015.11.26 (10-1574003) Composition for preventing or treating stroke or degenerative brain disease, 2016.01.19 (10-15882470000) Composition for the prevention or treatment of Inflammatory Bowel Disease comprising extract of Atractylodes spp, and Poncirus trifoliate 2016.05.03 (10-1620160) Composition comprising the combined extracts of Phlomis umbrosa, Astragalus membranceus, Discorea japonica, Acanthpanax senticosus and Angelica gigas for stimulating bone growth. 2016.07.14. (10-16414150000) Composition for preventing or treating stroke or degenerative brain disease 2016.07.26(10-16447550000) Composition for Preventing or Treating Short Stature Comprising Hordeum vulgare Extract. 2016.09.19. (10-16596670000) A composition comprising the complex extract of Poncirus trifoliata and Cinnamommum cassia for treating or preventing allergy desmatitis. 2017.05.15. (10-17382060000) Composition Comprising the Extract of polygonum cuspidatum for the Prevention or Treatment of Gastritis and Gastric ulce.r 2017.07.28. (10-17647410000) Composition Comprising L-argnine and Acanthopanax sessiliflorus Extract for Stimulating Bone Growth. 2017.08.28. (10-17740850000) A composition comprising the complex extract of Poncirus trifoliata and Cinnamommum cassia for treating or preventing allergy desmatitis. 2018.01.18 (10-18219250000) Compositions for Preventing, Improving or Treating Non-Alcoholic Fatty Liver Disease Comprising Combined Extracts of Peach Blossom and Lotus Leaf. 2018-08-01.(10-18862990000) Compositions for Preventing, Improving or Treating Obesity and Metabolic Diseases Comprising Combined Extracts of Peach Blossom and Water Chestnut, 2018.08.01 (10-18863140000) A pharmaceutical composition comprising the combined extract of Pueraria lobata and Scutellaria baicalensis for preventing or treating stroke and degenerative brain disease. 2018-08-01. (3056209, EU) Sceptridium ternatum for preventing or treating stroke and degenerative brain disease. 2018-08-01. (2926822, EU) A pharmaceutical composition comprising the extract of Sceptridium ternatum for preventing or treating stroke and degenerative brain disease. 2018-08-01. (10,172,895, US) Composition Comprising L-argnine and Acanthopanax sessiliflorus Extract for Stimulating Bone Growth. 2019-04-19.(10-19726390000) 2. 특허출원 Composition comprising the extract of crude drug complex having neuroprotective activity for preventing and treating stroke and neurodegenerative diseases 2007.07.24. (2007-552045 Japan) Composition comprising oleic acid and the use thereof 2008.02.21. (06700089.3 Europe) Composition comprising the extract of crude drug complex for stimulating bone growth 2009.06.05. (12/518,010 USA) The pharmaceutical composition comprising the extract of Astilbe chinesis for preventing and treating the degenerative brain disease 2012.02.15 (2012-0015418) pharmaceutical composition comprising the extract of Menispermum dauricum for preventing or treating the degenerative brain disease 2012.09.10 (2012-0099835) A pharmaceutical composition comprising the extract of Sceptridium ternatum for preventing or treating stroke and degenerative brain disease 2012.11.28. (2012-0135928) 전나무 잎 정유를 함유하는, 호흡기질환 관련 박테리아에 대한 항균 조성물 2013.01.10 (10-2013-0002839) 백출 및 탱자를 유효성분으로 포함하는 염증성 장질환 예방 또는 치료용 조성물 2013.03.29 (10-2013-0034397) A composition comprising the complex extract for preventing or treating stroke and degenerative brain disease. 2013.04.10 (10-2013-0039460) 백출 및 포공영을 유효성분으로 포함하는 염증성 장질환 예방 또는 치료용 조성물, 2013.04.24 (10-2013-0045621) A composition comprising the complex extract of Rehmannia glutinosa and Pueraria lobata for preventing or treating female menopausal disorder. 2013.06.11. (10-2013-0066592) A composition comprising the complex extract of Poncirus trifoliata and Cinnamommum cassia for treating or preventing allergy desmatitis. 2013.10.02 (10-2013-0117797) A pharmaceutical composition comprising the combined extract of Pueraria lobata and Scutellaria baicalensis for preventing or treating stroke and degenerative brain disease. 2013.10.08(10-2013-0119726) 맥아 추출물을 함유하는 성장 장애 예방 또는 치료용 조성물 2013.11.25 (10-2013-0143747) Anti-bacterial composition against bacteria related respiratory diseases, comprising essential oil from Abies holophylla. 2014.01.10 (10-2014-0003580) Composition Comprising L-argnine and Acanthopanax sessiliflorus Extract for Stimulating Bone Growth. 2014.03.26. (10-2014-0035188) Composition for the prevention or treatment of Inflammatory Bowel Disease comprising extract of Atractylodes spp, and Poncirus trifoliate. 2014.03.27 (10-2014-0035773) Pharmaceutical composition . 2014.04.23 (10-2014-0048585) 약학 조성물 2014.04.23 PCT/KR2014/003541 Composition comprising the combined extracts of Phlomis umbrosa, Astragalus membranceus, Discorea japonica, Acanthpanax senticosus and Angelica gigas for stimulating bone growth. 2014.06.27 (10-2014-0079851) Composition Comprising the Extract of polygonum cuspidatum for the Prevention or Treatment of Gastritis and Gastric ulcer. 2014.08.04. (10-2014-0099999) 갈근 및 황금의 복합 추출물을 유효성분으로 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물 2014.10.08 PCT/KR2014/009484 Composition for Preventing or Treating Short Stature Comprising Hordeum vulgare Extract. 2014.11.24. (10-2014-0164499) 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물 2015.03.17 (10-2015-0036783) Ｌ-아르기닌 및 오가피 추출물을 유효성분으로 포함하는 골길이 성장 촉진용 조성물, 2015.03.25(PCT/KR2015/002901) 고사리삼 추출물을 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물, 2015.06.26 (13858783.7, EU) Composition for preventing or treating stroke or degenerative brain disease. 2015.09.01 (10-2015-0123775) 고사리삼 추출물을 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물. 2015.09.11(14/648,240, US) 약학조성물, 2015.11.20(14788988.5. EU) 약학조성물, 2015.11.22(201480035673.9. CN) 지황 및 갈근의 복합 추출물을 함유하는 갱년기 증상의 예방 또는 치료용 조성물, 2015.12.10 (14/897,617, US) 지황 및 갈근의 복합 추출물을 함유하는 갱년기 증상의 예방 또는 치료용 조성물, 2016.01.06 (14811666.8, EU) 지황 및 갈근의 복합 추출물을 함유하는 갱년기 증상의 예방 또는 치료용 조성물, 2016.01.15 (201480040624.4, CN) 갈근 및 황금의 복합 추출물을 유효성분으로 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물, 2016.04.08 (15/018,388, US) 갈근 및 황금의 복합 추출물을 유효성분으로 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물, 2016.04.20 (14852440.8, EU) 맥아 추출물을 함유하는 성장 장애 예방 또는 치료용 조성물. 2016.05.24. (15/038,871, US) 맥아 추출물을 함유하는 성장 장애 예방 또는 치료용 조성물. 2016.05.25. (2016-534216, JP) 갈근 및 황금의 복합 추출물을 유효성분으로 함유하는 뇌졸중 및 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물, 2016.06.07 (CN) Pharmaceutical composition. 2016.06.28 (10-2016-0080883) 맥아 추출물을 함유하는 성장 장애 예방 또는 치료용 조성물. 2016.07.25. (201480074018.4, CN) Composition Comprising L-argnine and Acanthopanax sessiliflorus Extract for Stimulating Bone Growth. 2016.08.22 (10-2016-0106345) L-아르기닌 및 오가피 추출물을 유효성분으로 포함하는 골길이 성장 촉진용 조성품. 2016.11.18. (20158002746.2) 도화 추출물 또는 이의 분획물을 포함하는 대사성 질환의 예방, 개선 또는 치료용 약학적 조성물, 2017.03.20 (10-2017-0034590) 새싹보리 추출물을 함유하는 골길이 성장 촉진용 조성물. 2017.04.04. (10-2017-0043854) A composition comprising the complex extract of Poncirus trifoliata and Cinnamommum cassia for treating or preventing allergy desmatitis. 2017.05.15 (10-2017-0059864) Composition Comprising the Extract of polygonum cuspidatum for the Prevention or Treatment of Gastritis and Gastric ulcer. 2017.07.28 (10-2017-0095956) 도화 및 마름 복합 추출물을 포함하는 비만 및 대사성 질환의 예방, 개선 또는 치료용 조성물. 2017.10.31. (10-2017-0143819) 도화 및 하엽 복합 추출물을 포함하는 비만 및 대사성 질환의 예방, 개선 또는 치료용 조성물. 2017.10.31. (10-2017-0143854) |
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| 국제논문 | |
| 1. Conti B, Park L, Calingasan N, Kim Y, Kim H, Bae Y, Gibson G, Joh T. 1999. Culture of astrocytes and microglia expression interleukin 18. Mol Brain Res 67:46-52. 2. Conti B, Sugama S, Kim Y, Tinti C, Kim H, Baker H, Volpe B, Attardi B, Joh T. 1999. Modulation of IL-18 Production in the adrenal cortex following acute ACTH or chronic corticosterone treatment. Neuroimmunomodulation 8:1-7. 3. Yeo J, Lee K, Kim H, Oh Y, Kim A, Kim S. 2000. The effects of PVA/Fibroin(PCF)-Blended spongy sheets on wound healing in rats. Biol Pharm Bull 23:1220-1223. 4. Sugama S, Kim Y, Baker H, Tinti C, Kim H, Joh T, Conti B. 2000. Tissue-specific expression of rat IL-18 gene and response to adrenocorticotropic hormone treatment. J Immunol 165:6287-6292. 5. Lee P, Lee J, Kim S, Lee M, Yagita H, Kim S, Kim H, Suk K. 2001. NO as an autocrine mediator in the apoptosis of activated microglial cells: correlation between activation and apoptosis of microglial cells. Brain Res 892: 380-385. 6. Suk K, Lee J, Hur J, Kim Y, Lee M, Cha S, Kim S, Kim H. 2001. Activation-induced cell death of rat astrocytes. Brain Res 900:342-347. 7. Suk K, Kim S, Kim H. 2001. Regulation of IL-18 production by IFNg and PGE2 in mouse microglial cells: Involvement of NF-kB pathways in regulatory processes. Immunol Lett 77:79-85. 8. Hur J, Soe Y, Kim B, Suk K, Sohn N, Kim H, Kwon H, Lee K, Kim S. 2001. Neuroprotecive and neurotrophic effects of Quuinic acids from Aster scaber in PC12 cells. Biol Pharm Bull 24:921-924. 9. Suk K, Chang I, Kim YH, Kim S, Kim JY, Kim H, Lee M. 2001. Interferon-gamma and tumor necrosis factor synergism in ME-180 cervical cancer cell apoptosis and necrosis. J Biol Chem 276:13153-13159. 10. Kim H, Kim Y, Kim S, Suk K. 2001. The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. Neurosci Lett 309:67-71. 11. Kim Y, Leem K, Park J, Lee P, Ahn D, Lee B, Park H, Suk K, Kim S, Kim H. 2001. Cytoprotective effect of Scutellaria baicalensis in CA1 hippocampal neurons of rats after global cerebral ischemia. J Ethnopharmacol 77:183-8. 12. Lee J, Hur J, Lee P, Kim J, Cho N, Kim S, Kim H, Lee M, Suk K. 2001. Dual role of inflammatory stimuli in activation-induced cell death of mouse microglial cells: initiation of two separate apoptotic pathways via induction of interferon regulatory factor-1 and caspase-11. J Biol Chem 276:32956-32965. 13. Hur J, Kim SY, Kim H, Cha S, Lee MS, Suk K. 2001. Induction of caspase-11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway. FEBS Lett 507: 157-162. 14. Lim B, Choue R, Park D, Kim H, Kim S, Wamada K, Sugano M. 2002. Effect of dietary level of pectin on immunoglobulin and cytokine production by mesenteric lymph node lymphocytes and interleukin-2 receptor in rats. Food Sci Technol Res 8:14-16. 15. Suk K, Kim S, Kim H. 2002. Essential role of caspase-11 in activation-induced cell death of rat astrocytes. J Neurochem 80:230-238. 16. Suk S, Kim S, Leem K, Kim Y, Park S, Hur J, Baek J, Lee K, Zheng H, Kim H. 2002. Neuroprotection by methanol extract of Uncaria rhynchophylla against global cerebral ischemia in rats: inhibition of cyclooxygenase-2 induction. Life Sci 70:2467-2480. 17. Choi C, Kim S, Kim H, Suk K, Whang J, Lee B, Kim S. 2002. (4-Methoxybenzylidene)-(3-methoxyphenyl) amine, a nitrogen analog of stilbene as a potent inhibitor of melanin production. Chem Pharm Bull 50:450-452. 18. Park H, Lee H, Lee H, Yoo Y, Lee H, Kim S, Leem K, Kim H, Seo J, Kim E, Lim S, Chung J. 2001. Decrease of the electroacupuncture-induced analgesic effects in nuclear factor-kappa B1 knockout mice. Neurosci Lett 319:141-144. 19. Leem K, Park S, Lee D, Kim H. 2002. Lovastatin increases longitudinal bone growth and bone morphogenetic protein-2 levels in the growth plate of Sprague-Dawley rats. Eur J Pediatr 161:406-407. 20. Lee S, Choi S, Kim H, Hwang J, Lee B, Gao J, Kim S. 2002. Mulberroside F isolated from the leaves of Morus alba inhibits melanin biosynthesis. Biol Pharm Bull 25:1045-1048. 21. Park S, Lee H, Hur J, Kim S, Kim H, Park J, Cha S, Kang S, Cho G, Choi W, Suk K. 2002. Hypoxia induces nitric oxide production in mouse microglia via p38 mitogen-activated protein kinase pathway. Brain Res Mol Brain Res 107:9-16. 22. Koketsu M, Choi S, Ishihara H, Lim B, Kim H, Kim S. 2002. Inhibitory effects of 1,3-selenazol-4-one derivatives on mushroom tyrosinase. Chem Pharm Bull 50:1594-1596. 23. Cho K, Kang S, Kim E, Kim H, Lee Y, Chen J. 2002. The contents of calcium and phosphorus in Korean and Chinese enteral solutions and estimated daily intakes of patients undergoing long-term enteral nutrition. J ARAHE 9:11-17. 24. Leem K, Park S, Lee D, Boo Y, Cho K, Lim J, Jeon H, Park H, Chung J, Kim H. 2003. Effects of Jaoga-Yukmiwon, a Korean herbal medicine, on chondrocyte proliferation and longitudinal bone growth in adolescent male rats. Phytother Res 17:1113-1116. 25. Kim J, Son D, Lee P, Lee K, Kim H, Kim S. 2003. Ethyl acetate soluble fraction of Cnidium officinale Makino inhibits neuronal cell death by reduction of excessive nitric oxide production in lipopolysaccharide-treated rat hippocampal slice cultures and microglia cells. J Pahrmacol Sci 92:74-78. 26. Lee J, Son D, Lee P, Kum D, Shin M, Jang M, Kim C, Kim Y, Kim S, Kim H. 2003. Protective effect of methanol extract of Uncaria rhynchophylla against excitotoxicity induced by N-Methyl-D-Aspartate in rat Hippocampus. J Pahrmacol Sci 92:70-73. 27. Lee J, Son D, Lee P, Kum D, Shin M, Jang M, Kim C, Kim Y, KIm S, Kim H. 2003. Alkaloid fraction of Uncaria rhynchophylla protects against N-methyl-D-aspartate-induced apoptosis in rat hippocampal slices. Neurosci Lett 348:51-55. 28. Lee P, Son D, Lee J, Kim Y, Kim H, Kim S. 2003. Excessive production of nitric oxide induces the neuronal cell death in lipopolysaccharide-treated rat hippocampal slice culture. Neurosci Lett 349:33-36. 29. Kim J, Lee P, Son D, Kim H, Kim S. 2003. Falcarindiol inhibits nitric oxide-mediated neuronal death in lipopolysaccharide-treated organotypic hippocampal cultures. Neuroreport 14:1941-1944. 30. Lee H, Kim Y, Kim H, Kim S, Noh H, Kang S, Cho G, Choi W, Suk K. 2003. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J 17:1943-1964. 31. Lee B, Choi Y, Kim H, Kim S, Hahm D, Lee H, Shim I. 2003. Protective effects of methanol extract of Acori graminei rhizome and Uncariae ramulus et Uncus on ischemia-induced neuronal death and cognitive impairments in the rat. Life Sci 74:435-450. 32. Choi S, Kim S, Hwang J, Lee B, Kim H, Kim S. 2004. Benzylamide derivative compound attenuates the ultraviolet B-induced hyperpigmentation in the brownish guinea pig skin. Biochem Pharmacol 67:707-715. 33. Hur J, Lee P, Kim H, Kang I, Lee K, Kim S. 2004. (-)-3,5-Dicaffeoyl-muco-quinic acid isolated from Aster scaber contributes to the differentiation of PC12 cells; through tyrosine kinase cascade signaling. Biochem Biophys Res Commun 313:948-953. 34. Baek S, Bu Y, Kim H, Kim H. 2004. Telomerase induction in astrocytes of Sprague-Dawley rat after ischemic brain injury. Neurosci Lett 363:94-96. 35. Son D, Lee P, Lee J, Kim H, Kim S. 2004. Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. Eur J Plarmacol 493:99-102. 36. Kim H. 2005. Neuroprotective herbs for stroke therapy in traditional Eastern medicine. Neurol Res 27:287-301. 37. Bu Y, Jin Z, Park S, Baek S, Rho S, Ha N, Park S, Kim S and Kim H. 2005. Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats. Phytother Res 19:167-169. 38. Lee P, Hur J, Lee J, Kim J, Jueun J, Kang I, Kim S, Kim H. 2006. 15,16-Dihydrotanshinone I suppresses the activation of BV-2 cell, a murine microglia cell line, by lipopolysaccharide. Neurochem Int 48:60-66. 39. Oh M, Park C, Huh Y, Kim H, Kim H, Kim H, Bae H, Ahn D, Oark W, Park S. 2006. The effects of BR003 on memory and cell proliferation in the dentate gyrus of rat hippocampus. Biol Pharm Bul. 29:813-816. 40. Lee D, Ha N, Bu Y, Choi H, Park Y, Kim Y, Kim M, and Kim H. 2006. Neuroprotective effect of Buddleja officinalis extract on transient middle cerebral artery occlusion in rats. Biol Pharm Bull 29:1608-1612. 41. Chung H, Kim E, Lee D, Seo S, Ju S, Lee D, Kim H and Park S. 2007. Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology 148:149-159. 42. Bu Y, Rho S, Kim J, Kim M, Lee D, Kim S, Choi H, Kim H. 2007. Neuroprotective effect of tyrosol in transient focal cerebral ischemia in rats. Neurosci Lett 414:218-221 43. Kim M, Choi J, Lim J, Kim D, Shin T, Boo Y, Kim S, Kim H, Ha E, Park H, Kim J, Lim H, Kim E, Kim J, Leem K. 2007. Protective effects of a novel herbal decoction in focal cerebral ischemia a rodent model. Neurol Res 29:S16-S22. 44. Kim J, Chung SY, Park S, Park JH, Byun S, Hwang M, Oh DS, Choi H, Kim MY, Bu YC, Doré S, Whang WW, Kim H. 2008. Enhancing effect of HT008-1 on cognitive function and quality of life in cognitively declined healthy adults: a randomized, double-blind, placebo-controlled, trial. Pharmacol Biochem Behav. 90:517-524. 45. Kim YT, Yi YJ, Kim MY, Bu Y, Jin ZH, Choi H, Doré S, Kim H. 2008. Neuroprotection and enhancement of spatial memory by herbal mixture HT008-1 in rat global brain ischemia model. Am J Chin Med 36:287-299. 46. Hwang KY, Oh YT, Yoon H, Lee J, Kim H, Choe W, Kang I. 2008. Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells. Neurosci Lett 444:264-269. 47. Oh YT, Lee JY, Lee J, Kim H, Yoon KS, Choe W, Kang I. 2009. Oleic acid reduces lipopolysaccharide-induced expression of iNOS and COX-2 in BV2 murine microglial cells: possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-kappaB signaling pathways. Neurosci Lett. 464: 93-97. 48. Heo H, Shin Y, Cho W, Choi Y, Kim H, Kwon YK. 2009. Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis. J Ethnopharmacol 122:20-27. 49. Yune TY, Lee JY, Cui CM, Kim HC, Oh TH. 2009. Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats. J Neurochem110:1276-1287. 50. Jamarkattel-Pandit N, Pandit NR, Kim MY, Park SH, Kim KS, Choi H, Kim H, Bu Y. 2009. Neuroprotective effect of defatted sesame seeds extract against in vitro and in vivo ischemic neuronal damage. Planta Med 76:20-6. 51. Kim MY, Park Y, Pandit NR, Kim J, Song M, Park J, Choi HY, Kim H. 2010. The herbal formula HT042 induces longitudinal bone growth in adolescent female rats. J Med Food 13: 1376–1384. 52. Kim J, Kim MY, Leem KH, Moon S, Jamakattel-Pandit N, Choi H, Kim H, Bu Y. 2010. Key compound groups for the neuroprotective effect of roots of Polygonum cuspidatum on transient middle cerebral artery occlusion in Sprague-Dawley rats. Nat Prod Res 24:1214-1226. 53. Bu Y, Kwon S, Kim YT, Kim MY, Choi H, Kim JG, Jamarkattel-Pandit N, Doré S, Kim SH, Kim H. 2010. Neuroprotective effect of HT008-1, a prescription of traditional Korean medicine, on transient focal cerebral ischemia model in rats. Phytother Res 24:1207-1212. 54. Lee SH, Choi H, Kim H, Lee H, Sung YH, Kim SE, Chang HK, Shin MC, Shin MS, Kim CJ. 2010. Inhibitory effect of Angelicae tenuissimae radix on expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells. Neurol Res 32 Suppl 1:58-63. 55. Park S-H, Ryu S-N, Bu Y, Kim H, Simon JE, Kim K-S. 2010. Antioxidant components as potential neuroprotective agents in sesame (Sesamum indicum L.). Food Reviews International, 26:103-121. 56. Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS. 2011. Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion-induced memory impairments and chronic lipopolysaccharide infusion-induced memory impairments. J Ethnopharmacol 137:681-689. 57. Lee D, Park J, Yoon J, Kim MY, Choi HY, Kim H. 2012. Neuroprotective effects of Eleutherococcus senticosus bark on transient global cerebral ischemia in rats. J Ethnopharmacol 139:6-11. 58. Kim MY, Kim JY, Lim D, Lee D, Kim Y, Chang GT, Choi HY, Kim H. 2012. Skeletal Growth and IGF Levels in Rats after HT042 Treatment, Phytother Res. Phytotherapy Research 1771–1778 59. Lee SH, Kim JY, Kim H, Park SK, Kim CY, Chung SY, Chang GT. 2012. Amomum villosum induces longitudinal bone growth in adolescent female rats. J Tradit Chin Med 32:453-458 60. Choi SY, Kim YO, Son DW, Lee JS, Kim SH, Kim HC, Kim SY, Hur JY. 2012. 3-[2-(3,5-Dimethoxyphenyl)vinyl]furan protects hippocampal neurons against ischemic damage. 1472:32-37 61. Lee KJ, J JH, Y GS, Ham IH, BU YM, Kim HC, Cjoi H-Y. 2012. Endothelium-Independent Vasorelaxation Effects of Sigesbeckia glabrescens (Makino) Makino on Isolated Rat Thoracic Aorta. 10.1002/ptr.4874 62. Gaire BP, Kim HC, Park SH, Song M, Lim D, Choi HY, Kim NH, Park JY. 2012. Anti-obesity Effect of HT048, a Herbal Combination, in High Fat Diet-Induced Obese Rats. BMC Complement Altern Med. (17):14765-1477 63. KG Lee, IH Ham, GS Yang, MH Lee, YM Bu, HC Kim, HY Choi. 2013. Vasorelaxant effect of Prunus yedoensis bark. 13(31)1472-6882 64. MI Lee, H Kang, KJ Lee, GB Yang, IH Ham, YM Bu, HC Kim, HY Choi. 2013. The aerial part of Taraxacum coreanum extract has an anti-inflammatory effect on peritoneal macrophages in vitro and increases survival in a mouse model of septic shock. J Ethnopharmacol. 146(1)1-8 65. Gaire BP, Nirmala JP, DH Lee, JB Song, JY Kim, JY Park, SY Jung, HY Choi, HC Kim. 2013. Terminalia chebula extract protects OGD-R induced PC12 cell death and inhibits lps induced microglia activation. Molecules. 18:3529-3542 66. Lee K, Park G, Ham I, Yang G, Lee M, Bu Y, Kim H, Choi HY. Vasorelaxant effect of osterici radix ethanol extract on rat aortic rings. Evidence-Based Complementary and Alternative Medicine. 2013;2013:350964. doi: 10.1155/2013/350964. 67. Kim JY, Song M, Lee D, Song J, Park SW, Park J, Park S, Choi HY, Kim H. 2013 Effect of HT042, herbal formula, on longitudinal bone growth in spontaneous dwarf rats. Molecules. 18(11):13271-82 68. Gaire BP, Kim H. Neuroprotective effects of Fructus Chebulae extracts on experimental models of cerebral ischemia. Journal of Traditional Chinexe Medicine. 2014 Feb;34(1):69-75. PubMed PMID: 25102694. 69. Kim JY, Lee JI, Song M, Lee D, Song J, Kim SY, Park J, Choi HY, Kim H. Effects of Eucommia ulmoides Extract on Longitudinal Bone Growth Rate in Adolescent Female Rats. Phytother Research. 2014 Aug 2. doi: 10.1002/ptr.5195. [Epub ahead of print] PubMed PMID: 25087723. 70. Gaire BP, Moon SK, Kim H. Scutellaria baicalensis in stroke management: nature's blessing in traditional Eastern medicine. Chinese Journal of Integrative Medicine. 2014 Sep;20(9):712-20. doi: 10.1007/s11655-014-1347-9. Epub 2014 Apr 22. PubMed PMID: 24752475. 71. Kim HG, Jeong HU, Park G, Kim H, Lim Y, Oh MS. Mori folium and mori fructus mixture attenuates high-fat diet-induced cognitive deficits in mice. Evidence-Based Complementary and Alternative Medicine. 2015;2015:379418. doi: 10.1155/2015/379418. Epub 2015 Apr 7. PubMed PMID: 25945108. (SCIE) 72. Lee YH, Kim YS, Song M, Lee M, Park J, Kim H. A Herbal Formula HT048, Citrus unshiu and Crataegus pinnatifida, Prevents Obesity by Inhibiting Adipogenesis and Lipogenesis in 3T3-L1 Preadipocytes and HFD-Induced Obese Rats. Molecules. 2015 May 26;20(6):9656-70. doi: 10.3390/molecules20069656. PubMed PMID: 26016552. (SCIE) 73. Kim B, Lee K, Chinannai KS, Ham I, Bu Y, Kim H, Choi HY. Endothelium-Independent Vasorelaxant Effect of Ligusticum jeholense Root and Rhizoma on Rat Thoracic Aorta. Molecules. 2015 Jun 10;20(6):10721-33. doi: 10.3390/molecules200610721. PubMed PMID: 26065836. (SCIE) 74. JinGyu Choi, Gunhyuk Park, Hyo Geun Kim, Dal-Seok Oh, Hocheol Kim, Myung Sook Oh, In Vitro in Vivo Neuroprotective Effects of Walnut(Juglandis Semen) in Models of Parkinson’s Disease, International Journal of Molecular Sciences, 2016 Jan 15;17(1). Pii:E108.doir:10.3390 75. Lee SH, Kwak SC, Kim DK, Park SW, Kim HS, Kim YS, Lee D, Lee JW, Lee CG, Lee HK, Cho SM, Shin YJ, Lee JY, Kim H, Chang GT. Effects of Huang Bai (Phellodendri Cortex) and Three Other Herbs on GnRH and GH Levels in GT1-7 and GH3 Cells. Evidence-Based Complementary and Alternative Medicine. 2016 Jan 26;2016:9389028. Doi: 10.1155/2016/9389028. Pubmed PMID: 26925153. (SCIE) 76. Choi JH, Jang M, Kim EJ, Kim H, Ye SK, Cho IH, Oriental Medicine Woohwangchungsimwon Attenuates Kainic Acid-Induced Seizures and Neuronal Cell Death in the Hippocampus, Rejuvenation Research. 2016 Mar 16, Volume 19, Number 5DOl:10.1089. 77. Choi JG, Eom SM, Kim J, Kim SH, Huh E, Kim H, Lee Y, Lee H, Oh MS, A Comprehensive Review of Recent Studies on Herb-Drug Interaction: A Focus on Pharmacodynamic Interaction, Journal of Alternative and Complementary Medicine, 2016 Apr;22(4):262-79. doi: 10.1089 78. Lee D, Kim YS, Song J, Kim HS, Lee HJ, Guo H, Kim H, Effects of Phlomis umbrosa Root on Longitudinal Bone Growth Rate in Adolescent Female Rats, Molecules. 2016 Apr 7;21(4). pii: E461. doi: 10.3390 79. Lee YH, Jin B, Lee SH, Song M, Bae H, Min BJ, Park J, Lee D, Kim H, Herbal Formula HT048 Attenuates Diet-Induced Obesity by Improving Hepatic Lipid Metabolism and Insulin Resistance in Obese Rats., Molecules. 2016 Oct 25;21(11). pii: E1424 80. Song J, Lee SH, Lee D, Kim H. Astragalus Extract Mixture HT042 Improves Bone Growth, Mass, and Microarchitecture in Prepubertal Female Rats: A Microcomputed Tomographic Study, Evidence-Based Complementary and Alternative Medicine.. 2017 10 May, Volume 2017 (2017), Article ID 5219418, 7 pages. 81. Cho SM, Lee SH, Lee D, Lee JH, Chang GT, Kim H, Lee JY., The Korean herbal formulation Yukmijihwangtang stimulates longitudinal bone growth in animal models. BMC Complementary and Alternative Medicine 2 May 2017 DOI: 10.1186/s12906-017-1651-1 82. Han KH, Park JM, Jeong M, Han YM, Go EJ, Park J, Kim H, Han JG, Kwon O, Hahm KB, Heme Oxygenase-1 Induction and Anti-inflammatory Actions of Atractylodes macrocephala and Taraxacum herba Extracts Prevented Colitis and Was More Effective than Sulfasalazine in Preventing Relapse, Gut and Liver, 2017 Jun 27. doi: 10.5009/gnl16496 83. Lee D, Lee SH, Lee YH, Song J, Kim H, Astragalus Extract Mixture HT042 Increases Longitudinal Bone Growth Rate by Upregulating Circulatory IGF-1 in Rats., Evidence-Based Complementary and Alternative Medicine. 2017;2017:6935802. doi: 10.1155/2017/6935802. Epub 2017 Jun 20 84. Song J, Lee D, Min B, Bae JS, Chang GT, Kim H, Safety evaluation of Astragalus extract mixture HT042 and its constituent herbs in Sprague-Dawley rats., Phytomedicine. 2017 Aug 15;32:59-67. doi: 10.1016. Epub 2017 Mar 29 85. Hwang DS, Kim N, Choi JG, Kim HG, Kim H, Oh MS, Dangguijakyak-san ameliorates memory deficits in ovariectomized mice by upregulating hippocampal estrogen synthesis., BMC Complement Alternative Medicine. 2017 Nov 25;17(1):501. doi: 10.1186/s12906-017-2015-6. 86. Lee YH, Jin B, Lee S, Oh JY, Song J, Lee D, Kim YS, Kim H., A Herbal Formula HT051, a Combination of Pueraria lobata and Rehmannia glutinosa, Prevents Postmenopausal Obesity in Ovariectomized Rats., Evidence-Based Complementary and Alternative Medicine., Published online 2017 Dec 26. doi: 10.1155/2017/8641535 87. Lee SH, Lee HJ, Lee SH, Kim YS, Lee D, Chun J, Lee JY, Kim H, Chang GT., Effects of Huang Bai (Phellodendri Cortex) on bone growth and pubertal development in adolescent female rats., Chinese Medicine , Published online 2018 Jan 12. doi: 10.1186/s13020-017-0156-7 88. Lei Liu, Mary K. Vollmer, Victoria M. Fernandez, Yasmin Dweik, Hocheol Kim, Sylvain Dore. Korean Red Ginseng Pretreatment Protects Against Long-Term Sensorimotor Deficits After Ischemic Stroke Likely Through Nrf2. FRONTIERS IN CELLULAR NEUROSCIENCE. 23 March 2018, https://doi.org/10.3389/fncel.2018.00074 89. Huh E, Choi JG, Noh D, Yoo HS, Ryu J, Kim NJ, Kim H, Oh MS., Ginger and 6-shogaol protect intestinal tight junction and enteric dopaminergic neurons against 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine in mice. Nutrition Neuroscience., 2018 Sep 19:1-10. doi: 10.1080/1028415X 90. Liu L, Vollmer MK, Ahmad AS, Fernandez VM, Kim H, Doré S, Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism, Free Radical Biology & Medicine., 2018 Nov 17;131:98-114. doi: 10.1016/j.freeradbiomed 91. Kim YS, Park HJ, Kim H, Song J, Lee D., Gastroprotective Effects of Paeonia Extract Mixture HT074 against Experimental Gastric Ulcers in Rats., Evidence-Based Complementary and Alternative Medicine, 2019 Feb. 17. https://doi.org/10.1155/2019/3546258 92. Lee D, Lee SH, Cho N, Kim YS, Song J, Kim H., Effects of Eleutherococcus Extract Mixture on Endochondral Bone Formation in Rats., International Journal of Molecular Science. 2019 Mar 12;20(5). pii: E1253. doi: 10.3390/ijms20051253. 93. Lee D, Lee SH, Lee M, Lee SH, Shin YJ, Lee JY, Kim H, Kim YS, Song J., Effects of Siwu decoction on chondrocyte proliferation of growth plate in adolescent rats., J Ethnopharmacol. 2019 May 23;236:108-113. doi: 10.1016/j.jep.2019.01.048. Epub 2019 Mar 5. 94. Lei Liu, Mary K. Vollmer, Abdullah S. Ahmad, Victoria M. Fernandez, Hocheol Kim, ylvain Doré. Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism. Free Radic Biol Med . 2019 Feb 1; 131: 98–114. doi: 10.1016/j.freeradbiomed.2018.11.017 95. Donghun Lee,Kim YS, Song J, Hocheol Kim. Neuroprotective Effects of Musk of Muskrat on Transient Focal Cerebral Ischemia in Rats. 2019 Jun 25. doi: 10.1155/2019/9817949 96. Song J,Kim YS,Dong Hwan Lee,Sung Hyun Lee,Hyo Jin Park,Donghun Lee, Hocheol Kim. Neuroprotective effects of oleic acid in rodent models of cerebral ischaemia. 2019 Jul 249: 10732. doi: 10.1038/s41598-019-47057-z. 97. Song J,Kim YS, Linae Kim, Hyo Jin Park, Donghun Lee, Hocheol Kim. Anti-Obesity Effects of the Flower of Prunus persica in High-Fat Diet-Induced Obese Mice. 2019 Sep; 11(9): 2176. doi: 10.3390/nu11092176 98. Lei Liu, Mary K. Vollmer, Marie G. Kelly,Victoria M. Fernandez, Tyler G. Fernandez, Hocheol Kim, Sylvain Doré. Reactive Gliosis Contributes to Nrf2-Dependent Neuroprotection by Pretreatment with Dimethyl Fumarate or Korean Red Ginseng Against Hypoxic-Ischemia: Focus on Hippocampal Injury. 2019 Sep; 57(1):105-117. 10.1007/s12035-019-01760-0 99. Sung Hyuk Heo, Song J, Bum Joon Kim, Hocheol Kim, Dae-Il Chang. Rationale and design to assess the efficacy and safety of HT047 in patients with acute ischemic stroke: A multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase II trial. 2019 Oct; 98(43): doi: 10.1097/MD.0000000000017655 100. Song J, a Seon-mi Shin, Hocheol Kim. Efficacy and safety of HT048 and HT077 for body fat and weight loss in overweight adults: A study protocol for a double-blind, randomized, placebo-controlled trial. 2019 Nov; 98(45): doi: 10.1097/MD.0000000000017922 101. Song J, Seung Hwan Lee, Hocheol Kim. Efficacy and safety of HT080 for lower urinary tract symptoms associated with benign prostatic hyperplasia: A study protocol for a randomized, double-blind, placebo-controlled trial. 2019 Nov; 98(45): doi: 10.1097/MD.0000000000017848. |
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| 1. 성장촉진 추출물 및 이를 함유하는 약학적 제재(10-0404455), ㈜파진바이오, 2003.05 2. 신경세포 보호활성이 있는 복합생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2004.06 3. 성장촉진 추출물 및 이를 함유하는 약학적 제재(10-0404455), ㈜파진바이오, 2004.12 4. 신경보호작용을 갖는 황금추출물 및 이를 함유하는 약학적 제제(10-00364383), ㈜뉴메드, 2007.12 5. 신경세포 보호활성이 있는 복합생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2009.07 6. 신경세포 보호활성이 있는 복합생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2010.08 7. 뇌졸증 및 퇴행성 신경질환 예방 및 치료 효과를 갖는 복합생약재 추출물을 포함하는 조성물(10-0874187), ㈜뉴메드, 2011.03 8. 생약복합제 조성물을 함유하는 골길이 성장 촉진용 조성물(10-0847343), ㈜뉴메드 , 2011.05 9. 황기 생약추출물 또는 이로부터 분리된 에틸아세테이트 분획물을 함유하는 골길이 성장 장애 치료 및 예방용 약학 조성물(10-0997215), ㈜뉴메드 , 2011.05 10. 신경세포 보호활성이 있는 복합생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드 , 2011.07 11. 뇌졸증 및 퇴행성 신경질환 예방 및 치료 효과를 갖는 복합생약재 추출물을 포함하는 조성물(10-0874187), ㈜뉴메드, 2011.09 12. 생약복합제 조성물을 함유하는 골길이 성장 촉진용 조성물(10-0847343), ㈜뉴메드, 2011.11 13. 황기 생약추출물 또는 이로부터 분리된 에틸아세테이트 분획물을 함유하는 골길이 성장 장애 치료 및 예방용 약학 조성물(10-0997215), ㈜뉴메드, 2011.11 14. 신경세포 보호활성을 갖는 올레산을 함유하는 조성물(10-0756890), ㈜뉴메드, 2011.12 15. 신경세포 보호활성을 갖는 올레산을 함유하는 퇴행성뇌질환의 예방 및 개선용 건강기능식품(10-0746592), ㈜뉴메드, 2011.12 16. 신경세포 보호활성이 있는 복합생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2012.07 17. 신경세포 보호활성을 갖는 올레산을 함유하는 조성물(10-0756890), ㈜뉴메드, 2012.12 18. 신경세포 보호활성을 갖는 올레산을 함유하는 퇴행성뇌질환의 예방 및 개선용 건강기능식품(10-0746592), ㈜뉴메드, 2012.12 19. 생약복합제 추출물을 함유하는 골길이 성장 촉진용 약학적 조성물(10-0851855), ㈜뉴메드, 2013.04 20. 생약복합제 추출물을 함유하는 성장 촉진용 조성물, 신경세포 보호활성이 있는 복합 생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2013.07 21. 생약복합제 추출물을 함유하는 골길이 성장 촉진용 약학적 조성물(10-0851855), ㈜뉴메드, 2013.12 22. 신경세포 보호활성을 갖는 올레산을 함유하는 퇴행성뇌질환의 예방 및 개선용 건강기능식품(10-0746592), ㈜뉴메드, 2013.12 23. 생약복합제 추출물을 함유하는 골길이 성장 촉진용 약학적 조성물(10-0851855), ㈜뉴메드, 2014.10 24. 신경세포 보호활성이 있는 복합 생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2014.10 25. 겨울철 감기 예방을 위한 기능성 원료개발(노하우), ㈜뉴메드,2014.11 26. 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물(10-2015-0036783), ㈜뉴메드, 2015.03 27. 겨울철 감기예방을 위한 기능성 원료개발(노하우), 2015.09 28. 신경세포 보호활성이 있는 복합 생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-0592488), ㈜뉴메드, 2015.11 29. 생약복합제 추출물을 함유하는 골길이 성장 촉진용 약학적 조성물(10-0851855), ㈜뉴메드, 2015.11 30. 신경세포 보호활성이 있는 복합 생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-592488) , ㈜뉴메드, 2016.02 31. 생약복합제 추출물을 함유하는 골길이 성장 촉진용 약학적 조성물(10-851855), ㈜뉴메드, 2016.02 32. 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물(10-2015-0036783), ㈜뉴메드, 2016.04 33. 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물(10-2015-0036783), ㈜뉴메드, 2017.04 34. 신경세포 보호활성이 있는 복합 생약제 추출물을 포함하는 퇴행성 뇌질환의 예방 및 치료용 조성물(10-592488), ㈜뉴메드, 2017.04 35. 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물(10-2015-0036783), ㈜뉴메드, 2018.04 |
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